Forge

Nature has evolved gene cassettes and biosynthetic pathways that carry out multistep chemical reactions without the need for purification of intermediates. ErebaGen’s Forge platform makes minimal modifications to these pathways, enabling the production of unnatural products or the incorporation of non-native building blocks into natural scaffolds. Key advantages of this technology include:

• Pathway modifications performed outside the cell, avoiding slow development cycles in slow growing organisms
• Parallel modifications, enabling multiple pathway modifications simultaneously
• Easy transfer to heterologous hosts
• Replacement of multi-step organic synthesis with sustainable fermentation
• Facilitates the creation of molecules with enhanced properties