Mine:
Discovering novel sustainable chemicals for a range of uses
Nature is the source for 50% of all medicines and 25% of agrochemicals, yet this is achieved with only a tiny fraction of bacterial genomic capacity, because most bacterial pathways are inactive when their hosts are cultivated in the lab. ErebaGen’s Mine platform activates these pathways through genetic engineering to create libraries of bioactive natural compounds. Key advantages of our platform include:
- Circumventing rediscovery of known compounds using advanced computational tools
- Straightforward production of compounds in assayable quantities via targeted transcriptional activation
- Automated creation of several hundred compounds per month
- Hit rates of 25% in industrial bioactivity screens
- Rapid scale-up for downstream investigation