Forge:
Building bacteria for the production of high value chemicals
Nature has evolved gene cassettes and biosynthetic pathways
that carry out multistep chemical reactions without the need for purification
of intermediates. ErebaGen’s Forge platform makes minimal interventions to
these pathways, enabling the production of unnatural products or the
incorporation of non-native building blocks into natural scaffolds. Key
advantages of this technology include:
- Parallelised,
yeast-based genetic engineering platform accelerates manipulation of pathways
from slow-growing bacteria
- Facile
transfer to optimised hosts for high-level production
- Replacement
of expensive and wasteful multi-step synthetic processes with cheap, efficient
and sustainable fermentation
- Increasing
access to life-saving medicines in developing economies